Current Issue : October-December Volume : 2019 Issue Number : 4 Articles : 1 Articles
Datura metel is one of the fundamental herbs used in traditional medicine systems. Datura has tremendous uses. It is rich source of atropine and hyoscyamine. Atropine was isolated from plant leaves. Isolated goat tracheal chain preparation was used for calculating pA2 value instead of using laboratory animals. The pA2 was measured by Schild plot method using cumulative dose response curve of isolated atropine. This study conclude that isolated atropine have low pA2 value as compared to standard and demonstrate that goat trachea is an suitable alternative for pAx calculations....
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